Diffuse hepatic parenchymal lesions is a descriptive term for abdominal ultrasound or abdominal CT examination of the liver. The causes of diffuse hepatic parenchymal lesions include fatty liver, viral hepatitis, etc., which are caused by different etiologies and are treated with different medications. 1. Fatty liver: patients with diffuse hepatic parenchymal lesions, no need to take medication, by changing the diet, patients can often get relief, patients need to low-fat and low-cholesterol diet, avoid greasy spicy stimulating food, eat vitamin-rich foods, and insist on aerobic exercise every day. 2. Viral hepatitis: patients cause diffuse lesions of liver parenchyma, need to carry out antiviral and hepatoprotective treatment, clinical often choose entecavir for antiviral treatment, glutathione, glycyrrhizic acid for hepatoprotective treatment, but must be used under the guidance of a doctor. If the patient has any discomfort, go to the hospital in time, do not be careless, so as not to delay the treatment.