Polycystic ovary syndrome treatment

  Treatment of polycystic ovary syndrome 1. Improve lifestyle, eat less fatty food, strengthen exercise and control weight.  2, because patients with polycystic ovary syndrome are prone to metabolic diseases and cardiovascular diseases, they need to check relevant tests such as liver function, kidney function, blood lipids, blood glucose, insulin, including nail function.  PCOS is a disorder of ovulation, without ovulation there is no progesterone production, the endometrium will be under the effect of single estrogen for a long time, which will lead to irregular blood outflow or endometrial lesions. What is lacking can be supplemented by progesterone.  For your understanding, the following is my summary of the types of progestins. There are three major types of progestins: (1) The first type is the oral progestins: progesterone, dydrogesterone, and medroxyprogesterone. For progestin supplementation, not only must the dose be given in sufficient quantity, but the duration of use must also be achieved in order to adequately prevent the occurrence of endometrial cancer. Dose of progestin (daily endometrial dose): progesterone 200-300mg/day, medroxyprogesterone 5-10mg/day, dydrogesterone 10-20mg/day; time of progestin use: if progestin is used monthly for 7 days the incidence of endometrial cancer is 3%-5%, for 10 days the incidence is 2%, and for more than 12 days the incidence is 0; (2) The second category is compounded short-acting oral contraceptives (2) The second type is the compounded short-acting oral contraceptive pill: it is a combination of estrogen and progestin, but the progestin activity is the strongest, and its progestin activity is more than ten times that of estrogen, so it can also be seen as a highly effective progestin, so it can also be used to regulate menstruation.  PCOS patients can take progestin supplements in the second half of each monthly cycle or for 40 days without a period, after pregnancy has been ruled out. As long as it is ensured for at least 2 months that the endometrium can be fully transformed by progestin, endometrial lesions can be prevented (another purpose of relaxing to 40 days is that patients usually recover their periods on their own by losing weight and improving their lifestyle, and if they already have regular periods, they do not need progestin supplementation); compounded short-acting oral contraceptives can also be used, which can lower androgens in patients with high androgens. It can also protect the endometrium (in compound short-acting oral contraceptives, ethinyl estradiol can increase sex hormone binding protein, thus reducing free androgens; the contraceptives contain high-efficiency estrogen and progestin, so they can inhibit the gonadal axis, inhibit follicular development and reduce LH, because follicular membrane cells produce androgens from cholesterol under the action of LH, androgens enter granulosa cells, and FSH promotes aromatase activity, which converts androgens into estrogens. This is the two cell-two gonadotropic theory. (Therefore, when LH is lowered with the pill, androgens are also lowered). You can try to stop using the pill for 3 to 6 months for observation, because PCOS is a lifelong disease and cannot be eliminated from the root, so if your menstruation is still disordered, you will need to treat again with the pill or progestin.