HCY is homocysteine, early pregnancy homocysteine 12.7 μmol / L, can indicate elevated HCY, can be given folic acid, vitamin B for treatment, or a combination of heparin, aspirin anticoagulation. Elevated HCY stimulates the release of free radicals, damages vascular endothelial cells, induces the release of various coagulation factors, induces placental microthrombosis and meconium vascular necrosis, and leads to insufficient oxygen and blood supply to the placenta. Supplementation with folic acid and B vitamins, especially small doses of folic acid, can bring down HCY, and at the same time can promote the development of the nervous system. If HCY is elevated and a hypercoagulable thrombotic state has developed as measured by coagulation function and other measurements, anticoagulation therapy with drugs such as heparin and aspirin needs to be given. In addition, the specific medication should be under the guidance of a doctor, and should not be taken arbitrarily by oneself.