Tubular adenoma of the ascending colon with low-grade intraepithelial neoplasia usually requires treatment. Tubular adenoma of the ascending colon with low-grade intraepithelial neoplasia, i.e., pathologic biopsy results, is a precancerous lesion; resection is recommended for patients who have not been resected, and patients who have been resected need to undergo regular follow-up. If the pathologic biopsy tissue is a pedunculated polyp, then common polypectomy can be performed directly under colonoscopy; if it is a flat, raised, non-pedunculated polyp, endoscopic mucosal resection (EMR) can be performed; if it is a widely basal polyp, endoscopic submucosal dissection (ESD) is recommended; if it invades to the muscularis propria, then surgical intervention is considered. If the polyp has not been removed before the pathology results are reported, the resection should be performed as early as possible; if the pathology results are reported after the resection, the colonoscopy needs to be reviewed in 3 to 6 months, and the treatment plan should be adjusted according to the results. Patients must be in regular hospitals, under the guidance of professional doctors to rationalize the treatment.