Painful urination, the possible causes are as follows: 1, acute urinary tract infection, which can cause pain during urination, accompanied by increased urethral secretions or urinary burning, hematuria, and so on. It is recommended to conduct a urine test or urethroscopy to further rule out the existence of acute infection of the urethra.2, urethral stones, stone obstruction in the urethra, can cause painful urination, and can be accompanied by bleeding during urination. The stone blockage is more obvious can cause urinary difficulty or can not urinate the situation, need to carry out urethroscopy to clarify.3, sexually transmitted diseases, often seen in unclean sexual contact, can cause gonococcus, mycoplasma, chlamydia and other infections. After the infection can cause painful urination accompanied by a large amount of urethral discharge, need to carry out relevant sexually transmitted infections, such as gonococcal culture, mycoplasma, chlamydia examination.