Black acne marks may be the pigmentation left after the acne inflammation is relieved. To remove black acne marks, you can apply medication such as vitamin E milk, cumenex cream ointment, and mucopolysaccharide polysulfate cream. 1. Vitamin E Milk: The main ingredient is Vitamin E. Patients can apply Vitamin E Milk on the black acne marks, which can improve the antioxidant property of the skin, speed up the metabolism of the skin, and improve the deposition of melanin in the skin area, so as to achieve the effect of removing black acne marks. 2. Centella Asiatica Cream Ointment: It belongs to Chinese medicines. The main ingredient is the total glycoside of Centella asiatica. It has the effect of promoting the healing of wounds. After applying this drug, patients can improve local melanin deposition, reduce the degree of local melanin deposition on the surface, so as to achieve the effect of fading black acne marks. 3. Mucopolysaccharide polysulfate cream: this drug is a fibrinolytic drug. After use, patients can promote cell synthesis and recovery of intercellular substances, while maintaining the ability of local moisture, thus promoting the regeneration of connective tissue, to remove the effect of black acne marks. It is recommended that patients seek medical advice in a timely manner and follow the doctor’s instructions, so as to avoid improper use of medication on the health of the body.