Dyspepsia in 6-year-old girls is mostly caused by dietary factors, excessive secretion of gastric acid, Helicobacter pylori infection, etc. It can be relieved by dietary adjustments and medication. 1. Dietary factors: mostly due to overeating, eating greasy and spicy food, parents need to pay attention to correcting bad eating habits, the principle is a small number of meals, do not overfill, moderate nutrition, less residue, less salt, less greasy, easy to digest, light, and so on. 2. Excessive secretion of gastric acid: excessive secretion of gastric acid can also appear indigestion, can follow the doctor’s instructions to use omeprazole, cimetidine and other drugs to inhibit the secretion of gastric acid, magnesium aluminum carbonate, calcium carbonate oral suspension, compound aluminum hydroxide and other medications to protect the gastric mucosa treatment. 3. Helicobacter pylori infection: when the stomach is infected by Helicobacter pylori, it can also cause dyspepsia, generally applying omeprazole, clarithromycin, amoxicillin, bismuth citrate, metronidazole and other medicines for the eradication of Helicobacter pylori treatment. Probiotics such as bifidobacteria and clostridium casei can also be used to regulate intestinal flora and improve gastrointestinal function. All of the above medications should be used under doctor’s supervision, avoid self-medication. When indigestion occurs in children, it is recommended to consult a specialist for evaluation and management.