Bilateral frontoparietal white matter abnormality is a diagnostic imaging description of abnormal signals in the white matter cells in the frontal lobe area of the brain, which may be a physiologic phenomenon or a result of pathologic factors. 1. Physiological phenomenon: Bilateral frontoparietal white matter abnormality is related to congenital development, which may be caused by the slow development of the child’s brain and the incomplete development of myelin sheaths, but it is still developing. This condition has no major impact on the child itself, and usually does not have clinical symptoms, so it does not require special treatment, and regular follow-up review of the cranial brain magnetic resonance can be. 2. Pathological factors: mainly due to the demyelination of the white matter of the brain, commonly found in immune system diseases, poisoning, metabolic diseases, etc., which may result in slurred speech, slow reaction, etc. The main treatments for the cause of the disease are immune preparations, hormones (e.g., methylprednisolone, dexamethasone, etc.), and medications that nourish the brain cells (e.g., cytosolic choline, cerebrin hydrolysate, etc.). For bilateral frontoparietal white matter abnormalities, it is recommended to go to the neurology department for active consultation and treatment after clarifying the cause of the disease. Do not take drugs blindly to avoid delaying the condition.