Coronary groove infection usually refers to the presence of inflammation and infection in the male’s coronal groove area, which usually causes itching, pain, oozing and redness and other symptoms. Men do not wash the foreskin for a long time, may lead to bacterial and fungal growth in the coronary groove area, easy to induce inflammatory infection, when the inflammatory material increases, the coronary groove area caused by stimulation, will cause itching, pain, redness, edema, and in severe cases, there will be vesiculation, oozing. After a long time without treatment, the infection continues to aggravate, may induce genitourinary infections, such as urethritis or prostatitis; therefore, diagnosed with inflammation of the coronary groove, should be timely treatment with medication, such as erythromycin ointment, clotrimazole ointment, and so on. When using medication, it is important to follow the doctor’s instructions, safe and reasonable use of medication, do not self-medication.