Plasma cell glans is the term used to describe plasma cell glansitis, the cause of which is unclear and may be related to a variety of factors such as friction and infection. Due to the stimulation of inflammatory mediators will lead to patients with symptoms such as flaking, glans lesions, itching, etc. If not treated in time when, may also appear urination difficulties and other symptoms. Patients with plasma cell glans can be treated with topical tacrolimus, topical mupirocin ointment, oral azithromycin and other medications under the direction of a doctor. For patients with more serious condition or long foreskin, they can take circumcision and other surgical methods for treatment. Once diagnosed with plasma cell glans, patients should go to the hospital for treatment in time to avoid delaying the condition. The application of the above drugs should be applied under the guidance of professional physicians.