Once hepatitis B is fibrotic, it can progress to an irreversible degree and develop into cirrhosis if left unchecked without systematic antiviral treatment and anti-fibrotic therapy. Further progression of cirrhosis can lead to liver cancer and liver failure, with a poor prognosis. However, if antiviral treatment is indicated in the early stage of liver fibrosis, active antiviral treatment can effectively improve the degree of liver fibrosis, while some anti-fibrotic drugs, such as turtle nail soft liver tablets and Anluo Fibrillation Pill, can be used to reverse the degree of cirrhosis and liver fibrosis, or even disappear completely. Without systematic treatment, liver fibrosis gradually progresses to an irreversible degree, or even to the degree of cirrhosis, which may lead to irreversible and serious liver damage, affecting prognosis, as well as survival and reducing quality of life.