Pancreatic cancer will lead to edema of lower limbs, and generally there will be serious swelling of lower limbs in the late stage. If cardia cancer patients have lower limb edema, it may be due to long-term bed-ridden, obstructed blood circulation leading to lower limb edema, and further examination is needed as early as possible to avoid metastasis of malignant tumor lesions. Patients with pancreatic cancer consume a lot to the body in the late stage, due to the patients’ appetite loss, the nutrition required by the body is insufficiently supplemented, leading to malnutrition, causing hypoproteinemia and inducing lower limb edema. Patients should pay attention to low-salt diet in daily diet, elevate both lower limbs when resting, and massage for patients. Patients with cardia cancer should seek medical treatment in time after edema occurs, and carry out relevant treatment under the professional guidance of doctors.