Whether glutamyl transpeptidase is high to 90U/L is serious or not needs to be decided according to the nature of the disease, if it is fatigue, staying up all night and other physiological factors, it is not serious, on the contrary, if it is caused by the disease, it is more serious. The normal value of glutamyl transpeptidase is 0U/L~30U/L, and the test shows that the glutamyl transpeptidase value of 90U/L is high. High glutamyl transpeptidase may be related to physiological factors, such as prolonged severe fatigue, late night and other factors; it may also be related to myocardial infarction, liver diseases such as cirrhosis, biliary tract diseases such as bile duct obstruction, pancreatic diseases such as pancreatic cancer, alcoholism, medications such as chlorpromazine leading to liver injury and other disease factors. If the glutamyl transpeptidase is high to 90U/L due to physiological factors, it will usually return to normal slowly after conditioning; if it is due to disease factors, it will need symptomatic treatment to return to normal. If the patient’s symptoms are serious, or if the symptoms continue without improvement, the patient should go to the hospital in time for treatment.