A tetanus shot is required for a hand punctured by a barbecue stick. If the barbecue stick is deep, an anaerobic environment may be present, which favors the multiplication of Clostridium tetani. Tetanus is a very serious specific infection caused by Clostridium tetani, an anaerobic bacterium that is widespread in nature and requires an anaerobic environment to grow and multiply. Clostridium tetani may also be attached to iron or bamboo skewers used for barbecuing. If the wound where the skewer pierces the hand is deep, an anaerobic environment may occur, which is conducive to the reproduction of Clostridium tetani. After being infected by Clostridium tetani, the bacterium will produce endotoxin and exotoxin after multiplying in the body. Tetanus toxin will make the whole body appear a spasm, and even make the respiratory muscle and swallowing muscle spasm eventually leading to respiratory and cardiac arrest. Once this happens, the death rate is extremely high, so timely prevention is very important. It can be prevented by injecting tetanus antitoxin to neutralize the tetanus toxin in the body. If you have been pierced by a barbecue stick, go to the hospital and consult a doctor for tetanus vaccination.