Breast nodules have a higher chance of becoming cancerous, such as fibroid tumors and breast hyperplasia. Factors affecting the cancerous change of nodules include: 1. Cancer is related to living habits and the duration of the disease. Nodules may become cancerous with the passage of time without appropriate medical interventions or endocrine adjustments or changes in patients’ living habits; 2. Cancer is related to familial factors of cancer, and patients with a family history of breast cancer should be more careful when they have nodules. The chances of cancer in low-risk groups are smaller, while high-risk groups include: 1) early menarche; 2) late childbearing age; 3) women who do not breastfeed; 4) high-fat diet; 5) oral contraceptive pills and so on. A variety of factors can lead to breast lumps that become cancerous as the disease progresses. Individual nodules that are harder in texture have a slightly higher chance of becoming cancerous. Patients over 30 years of age with breast nodules are advised to undergo annual specialist palpation, with molybdenum follow-up and monitoring for some high-risk patients, and close follow-up especially for menopausal women over 40 years of age.