Acute tubular necrosis (ATN) is the most common type of acute renal failure, accounting for approximately 75% to 80% of cases. It is a clinical syndrome that occurs as a result of acute, progressive decompensation of renal function due to renal ischemia and/or nephrotoxic damage caused by various etiologies. The main manifestations are progressive azotemia due to a marked decrease in glomerular filtration rate, and imbalance of water, electrolyte and acid-base balance due to low renal tubular reabsorption and excretion function. The dietary principles of patients with tubular necrosis: 1, sodium intake: edema should be into a low-salt diet, so as not to aggravate edema, generally no more than 2g of salt per day is appropriate, prohibit pickled foods, less MSG and alkali, edema subsided, plasma protein close to normal, can resume the ordinary diet. 2. Protein intake: In renal failure syndrome, a large amount of plasma protein is excreted from the urine, and the human body is in a protein malnutrition state due to the decrease in protein, and hypoproteinemia makes the plasma colloid osmotic pressure drop, resulting in stubborn edema, and the resistance of the body also decreases. such as fish and meat. This helps to alleviate the hypoproteinemia and some of the ensuing comorbidities. However, a high protein diet can increase renal blood flow and glomerular filtration rate, putting the glomerular capillaries under high pressure, and also increase proteinuria with high protein intake, which can accelerate glomerulosclerosis. Therefore, for chronic, non-polar renal failure syndrome patients should consume a small amount of high-quality protein (0.7 ~ 1g/kg*d), as for the emergence of chronic renal impairment, it should be a low protein diet (0.65g/kg*d). 3, fat intake: tubular necrosis patients often have hyperlipidemia, which can cause arteriosclerosis and glomerular damage, sclerosis, etc., and therefore should be limited to animal offal, fatty meat, certain seafood and other cholesterol-rich and fatty food intake. 4, trace elements supplementation: because of tubular necrosis patients glomerular basement membrane permeability increases, in addition to the loss of protein in the urine, but also lost and protein combined with certain trace elements and hormones, resulting in the human body calcium, magnesium, zinc, iron and other elements lack, should be given appropriate supplementation. Generally, you can eat vitamin and trace element-rich vegetables, fruits, grains, seafood, etc. to supplement, eat more fruits and vegetables.