Long-term hemodialysis patients have a variety of complications, as follows: 1, hypertension: many patients combined with hypertension, treatment to actively control blood pressure; 2, infection: bacterial infections can generally occur, such as lung infections, urinary tract infections, and inevitably hepatitis C and B infections; 3, long-term dialysis: for example, after 5-10 years can appear joint pain, joint amyloidosis; 4, the Cardiovascular: for example, suffering from coronary heart disease and angina; 5. Malnutrition: long-term dialysis patients obviously lack nutrition, related to diet and dialysis loss; 6. Trace element changes: for example, aluminum toxicity, related to dialyzer and dialysis machine; 7. Neurological complications: for example, dizziness, headache, vascular spasm; 8. Digestive system problems: for example, indigestion, poor nausea, digestive bleeding; 9. Hematological system complications: such as anemia, thrombocytopenia; 10. Endocrine complications: such as active vitamin D3 deficiency, erythropoietin reduction, which require symptomatic treatment. Therefore, long-term hemodialysis can lead to problems of various systems, which need to be dealt with and treated in a timely manner.