The benefits of vasodilators include relief of local ischemia and reduction of peripheral resistance; the harms include vessel walls becoming weak and prone to rupture, thrombosis, and other side effects. 1. Benefits of vasodilators. Relieve local ischemia: For example, if there is a narrowing or occlusion of the blood vessels in the body, which will lead to symptoms of ischemia such as numbness, pain, edema, etc., then you can use this kind of drug to increase blood supply and relieve ischemic symptoms caused by narrowing of blood vessels. Reduce peripheral resistance: vasodilators can reduce peripheral resistance of blood vessels, reduce cardiac afterload; the use of intravenous vasodilators, can reduce the volume of return blood, reduce cardiac preload; positive significance to the prevention and treatment of heart failure, can improve the patient’s survival treatment, to prevent the heart is remodeling. 2.The bad side of vasodilators. Vascular wall becomes fragile and easy to rupture: vasodilatation, smooth muscle overextension, will make the wall of the blood vessel thin, in some of the blood vessel itself with lesions, it is easy to lead to rupture of the blood vessel bleeding, the serious can lead to death, such as the rupture of the abdominal aortic aneurysm. Thrombosis: After dilation, the blood vessels may form localized whirlpools, forming blood clots, and the dislodgment of blood clots may lead to embolism and other conditions. Other side effects: Vasodilatation may also cause blood pressure to drop too much, resulting in insufficient blood supply to the limbs and low blood pressure. In addition, vasodilatation may also result in a rich local blood supply, for example, resulting in increased intracranial pressure, which may cause dizziness and headaches; In conclusion, the use of vasodilator drugs must be taken under the guidance of a doctor, so that they can avoid side effects as much as possible and play their advantageous role.