Children with ventricular septal defects have a high probability of self-healing, generally around 30% within 1 year of age. In general, small perimembranous, membranous, and myocardial septal defects in the heart are more likely to heal on their own and have a higher probability of healing; the larger the defect, the lower the probability of healing. The larger the defect, the lower the probability of self-healing. Even if the defect fails to heal on follow-up, there is no need to worry too much. Currently, surgical treatment of ventricular septal defects is effective and has a high success rate, and the mortality rate is close to 0%. It is recommended to pay attention to the screening of fetal anomalies during the obstetric examination, and to carry out timely examination and treatment after problems arise to avoid delay.