The serologic method for testing anthrax is the detection of antipodocin antibodies and PA exotoxin antibodies, but the diagnostic significance of serologic tests is limited, and they are usually used only for screening, and bacterial culture of the specimen is the basis for confirming the diagnosis.
Serologic methods mainly detect the presence of antipodocin antibodies and PA exotoxin antibodies in serum through immunoblotting experiments, which are usually performed before the results of pathogenetic diagnosis, and have a certain degree of specificity and sensitivity.
In contrast, bacterial culture by collecting specimens of secretions, blood, and cerebrospinal fluid is a confirmatory test, and the diagnosis is confirmed if Bacillus anthracis is found.
When infected with B. anthracis, active treatment is required under the supervision of a doctor.