Babies with atrial septal defects can be treated with general therapy, surgery and interventional therapy. If there are complications such as atrial fibrillation, amiodarone and other medications can be prescribed. 1. General treatment: avoid cold and flu, and have regular checkups. Small atrial septal defects have a tendency to heal on their own, and most of them can be closed before the age of 2 years. 2. Surgery and interventional therapy: generally, atrial septal defects can be closed by surgery and interventional therapy before school age. 3. Drug treatment: some more serious atrial septal defects can be complicated by atrial fibrillation, in the absence of contraindications, amiodarone can be used to correct atrial fibrillation as prescribed by the doctor. It is recommended to pay attention to the reasonable adjustment of room temperature, appropriate adjustment of the baby’s clothing, to prevent colds and pneumonia. If the baby’s clinical manifestations are more obvious, it is necessary to consult a cardiothoracic surgeon in time, and follow the doctor’s instructions to evaluate and treat the baby with surgery in a limited period of time.