If the hand is often numb and awake at night, the following causes are mainly considered: First, the patient should be asked if there is any previous cerebral infarction, such as lobar infarction or lobar hemorrhage, ischemic-hypoxic encephalopathy, such as acute drug poisoning or carbon monoxide poisoning. The above-mentioned causes can cause secondary seizures manifesting as focal seizures, some sleep with numbness and discharge of the hand, this time you can go to the hospital to do an electroencephalogram examination to clarify. The second is to ask if the patient’s sleeping position is correct, if he or she is in a long-term lateral position, if he or she is in a long-term prone position, it is easy to cause pressure on the hand causing ischemia and hypoxia to manifest as limb numbness, and this time the numbness of the hand will be relieved after activity and turning over. Thirdly, if the patient often wakes up with numbness at night when sleeping, ask the patient if there are leg cramps, and some hypocalcemia patients show numbness in their hands, so they can have their blood calcium measured.