Stomach pain after taking tenofovir disoproxil fumarate tablets is mainly considered a side effect of the drug. Tenofovir disoproxil fumarate tablets are mainly used for the treatment of chronic hepatitis B patients with antiviral therapy, among the current oral antiviral drugs, the antiviral effect is relatively strong, the resistance rate is very low. Common side effects of the drug include gastrointestinal reactions such as nausea, vomiting or abdominal pain and diarrhea. Patients who experience severe gastrointestinal reactions are advised to seek prompt medical attention and change to other antiviral drugs under the guidance of clinicians. Therefore, patients taking tenofovir disoproxil fumarate tablets may experience gastrointestinal reactions such as nausea and vomiting, abdominal pain and diarrhea, it is recommended that patients take a light diet during the period of medication, do not overeat and drink, and regularly check the liver and kidney functions, and in the event of serious gastrointestinal reactions it is recommended that patients consult a doctor in time to treat the symptoms under the guidance of the doctor, so as to avoid delaying the condition. Drugs should be used in accordance with medical advice.