Pain in the urinary orifice, it is important to find the cause of the painful urination before effective treatment. If it is the inflammation of the urethra, clean the urethra, apply erythromycin ointment locally, drink more water and take anti-inflammatory drugs, it will soon be relieved. This condition generally does not require painkillers. If the pain is unbearable, you can give intra-anal diclofenac suppositories. If there is pain throughout the urethra, this may be a case of inflammation of the urethra. In this case, you should have a routine urine test to assess the severity of the inflammation, and you should drink more water, urinate more often, and take broad-spectrum antibacterial agents. If the pain in the urinary orifice is caused by a stone in the urethra, in this case the stone should be clamped out so that the pain in the urinary orifice will be relieved quickly, and after removing the stone, you must drink more water and take anti-inflammatory drugs.