Drinking knee pain may be caused by alcohol irritation, gouty arthritis, calcium loss, etc. You should consult a doctor in time to find out the cause. 1. Alcohol stimulation: If the concentration of alcohol in the blood is high after drinking, and alcohol is irritating, it may stimulate the knee joint and lead to knee pain. Patients can speed up the metabolism of alcohol and relieve the symptoms by drinking more water and moderate exercise. 2. Gouty arthritis: Gouty arthritis is a sterile inflammatory disease characterized by self-limiting and severe pain, with the main symptoms of redness, swelling, heat and pain in the joints, etc. So knee pain after drinking alcohol may be caused by gouty arthritis. 3. Calcium loss: Alcohol will lead to a decrease in the absorption rate of calcium in the bones, thus aggravating the loss of calcium in the knee joint, making the knee joint muscle tissue nutritional metabolic disorders, manifested as knee pain, tenderness, weakness, etc., so the knee pain after drinking alcohol may be caused by calcium loss. However, other factors can not be ruled out, it is recommended to consult a doctor in a timely manner, by the doctor to clarify the cause of the disease, to give targeted treatment.