Lateral ankle tendon pain may be caused by sprain, ligament injury, ankle bone fracture and other conditions, patients need to follow the medical advice for drug treatment, surgical treatment, general measures. 1. Sprain: within 72 hours after ankle sprain, patients need to apply ice locally and elevate the affected limb appropriately. Some patients can also use elastic bandage or inflatable immobilizer for compression, so as not to aggravate the swelling. Generally, no medication is needed for patients with minor sprains. If the symptoms are serious, anti-inflammatory and analgesic drugs such as ibuprofen, nimesulide and rofecoxib should be used as prescribed by the doctor. 2. Ligament injury: usually I degree injury patients need to use ibuprofen, acetaminophen and other analgesic treatment, and with local ice. For patients with second and third degree injuries, the ankle joint should be braked and rehabilitation exercises should be carried out. If the patient’s condition is more serious, arthroscopic minimally invasive surgery should be chosen. 3. Ankle bone fracture: patients with mild condition can be reset by manipulation and fixed with plaster. However, patients with severe fractures need to undergo surgical treatment. Usually, patients with lateral ankle fracture can use screws for fixation and regular review, actively cooperate with doctors for rehabilitation training. It is recommended that when symptoms of lateral ankle tendon pain occur, consult a doctor in time to identify the cause of the disease and carry out reasonable treatment.