Whether gallstones 1.5cm need surgery is analyzed according to the specific clinical manifestations. If the patient does not have any discomfort, non-surgical treatment can be carried out, and regular follow-up observation is sufficient. If the patient has typical right upper abdominal pain, nausea, vomiting and other symptoms, the need for timely surgery. 1. With or without symptoms: patients with stones 1.5cm, if there is no special performance without treatment; if the symptoms recur, and have abdominal pain, jaundice, biliary obstruction and other manifestations, in the case of conservative treatment is ineffective, we need to consider surgical treatment. 2. The presence of comorbid diseases: if gallstones 1.5cm combined with severe cholecystitis, gallbladder wall thickening (>0.3cm), calcified or porcelain gallbladder, this situation should be considered for surgical treatment. 3. The number of stones: If the simple gallstones 1.5cm, relatively not particularly serious. However, if the stones are multiple and occupy most of the gallbladder space, surgical treatment is required. 4. The patient’s general condition: whether the patient has had other surgeries, the patient’s age, whether the body can tolerate surgery, all need to be evaluated comprehensively. Overall, gallstones of 1.5cm are not particularly serious, and whether or not to operate should be assessed in conjunction with other factors, so consult a medical professional for specific advice.