Urinary microalbumin greater than 30mg/L may suggest that the kidney disease. However, we need to exclude the possibility of physiological proteinuria, such as fever, strenuous exercise, eating a large amount of high-protein food, etc. can lead to microalbuminuria. Therefore, the clinical need to improve the urinary ultrasound, renal function and other tests, and if necessary, improve the renal puncture biopsy to clarify the condition. Elevated urinary microalbumin can be seen in pathological conditions such as various types of kidney disease, urinary tract infections, urinary stones, etc.; it can also be seen in some physiological conditions, such as strenuous exercise, Nutcracker syndrome, fever, staying up all night, eating a lot of high-protein food. Patients need to follow the doctor’s instructions to improve autoimmune series, complement series, screening for infectious diseases, urine routine, urinary ultrasound and other tests to clarify the cause of elevated urinary microalbumin, and if necessary, improve the renal puncture biopsy, to further clarify the condition and guide the treatment. Urine microalbumin abnormal patients, it is recommended to go to the regular hospital for further diagnosis, as soon as possible to clarify the cause of the disease, early treatment.