What kind of medicine to take for rotting tongue needs to be combined with the cause of the disease, at present the clinical rotting tongue may be related to tongue ulcer, lingual inflammation and lichen planus to some extent, in the treatment of painkillers, antifungal drugs and immunosuppressant drugs can be chosen. 1. Tongue ulcers: tongue ulcers are a common disease that can lead to ulceration of the mucous membrane of the tongue and severe pain, usually choose pain-relieving drugs, such as lidocaine gel. 2. Tongue inflammation: Tongue inflammation is usually easy to appear in the front of the tongue, there will be spots of skin lesions, accompanied by burning pain as well as numbness and so on. Tongue inflammation may occur in patients with iron-deficiency anemia, and oral iron supplements, such as ferrous sulfate, are usually available. If it is caused by Candida infection, generally choose antifungal treatment, such as fluconazole and itraconazole. 3. lichen planus: patients with oral lichen planus will also have the phenomenon of pain, there will be lisping, usually can use topical drugs, such as calcium-modulated phosphatase inhibitors. If it is more serious generalized lichen planus, the choice of topical medication is not effective, you can use immunosuppressive drugs, such as methotrexate, cyclosporine. The tongue has a variety of causes, so it is not recommended to blindly treatment, you need to go to the hospital to do a detailed examination, after the diagnosis to take targeted treatment, the use of medication need to comply with the doctor’s instructions.