Nucleic acid testing generally refers to novel coronavirus nucleic acid testing, which can be done for dry throat. Dry throat is usually acceptable for nucleic acid testing. Dry throat does not affect the level of virus in body fluids and does not affect the accuracy of nucleic acid test results. However, if the throat is excessively dry, it may cause nausea, vomiting, and sore throat during the throat swabbing process. A dry throat can be relieved by drinking a little warm water 2 hours before the nucleic acid test to help replenish the body’s moisture. It is important to note that you should not chew gum, drink water or smoke for 30 minutes before the nucleic acid test. Sampling should be done with less swallowing and no throat clearing to avoid affecting the final result. If the nucleic acid test result is positive, you should go to the hospital in time to avoid adverse consequences.