Hepatitis B virus DNA 3.866E4 is not serious if it does not cause damage to liver function; if it causes more serious liver damage, treatment is needed. Hepatitis B virus DNA3.866E4 indicates that there is hepatitis B virus in the body, and the amount of virus is in a moderate degree of replication, the specific severity depends on whether the liver function is damaged, so you can check the liver function, liver, gallbladder, pancreas and spleen ultrasound to further clarify the liver function, if the liver function is completely normal, it suggests that the problem is not serious, and we recommend that you review it regularly. If the liver function is completely normal, it is not serious and regular review is recommended. If it has already caused elevated transaminase and bilirubin, or even caused liver fibrosis which is more serious, it is necessary to go to the hospital for active antiviral and hepatoprotective treatment. Hepatitis B virus DNA 3.866E4, it is recommended to actively consult the doctor for examination, according to the results of symptomatic treatment.