Focal low-grade intraepithelial neoplasia is an atypical hyperplasia of the local epithelial tissue, which is generally benign and does not require special treatment, and can be observed with regular follow-up. Focal low-grade intraepithelial neoplasia of the cervical epithelium indicates atypical proliferation of localized epithelial cells of the cervix, which may be caused by chronic inflammation. This lesion is generally benign, so the patient does not need to worry too much, can control the inflammation, remove the stimulus to make the low-grade intraepithelial neoplasia disappear. If the low-grade intraepithelial neoplasia is localized due to chronic irritation from cervical inflammation, the patient can control the chronic inflammation with medications such as amoxicillin. Amoxicillin has the potential to cause adverse reactions such as allergies in patients and needs to be used under medical supervision. Although focal low-grade intraepithelial neoplasia is a benign lesion, patients should also follow up regularly for observation and seek medical attention when problems arise.