Itchy skin all over the body may be related to urticaria, eczema, pruritus, scabies infection and other factors. Anti-allergy, glucocorticoid and other medications can be given. 1. Urticaria: Urticaria is an allergic reaction, considered to be related to various factors, it is recommended to find and get rid of allergens. Combined with oral loratadine, cetirizine and other antihistamines, can reduce the release of histamine. When the effect of antihistamine alone is not good, it can be combined with oral prednisone, which has anti-inflammatory effect and can quickly relieve the symptoms. 2. Eczema: Eczema may be caused by a combination of internal and external factors, resulting in the appearance of skin pimples, papules with itching. Antihistamines such as levocetirizine and desloratadine can be given or combined with oral hormonal drugs such as dexamethasone and immunosuppressants such as cyclosporine. 3. Pruritus: Pruritus includes generalized pruritus, senile pruritus, winter pruritus, summer pruritus, and limited pruritus. Such as generalized pruritus, can lead to patients with generalized skin itching. Isoprinosine and cyproheptadine can be given, together with calcium and vitamin C and other drugs, which can help to relieve the symptoms. 4. Scabies infection: Scabies infection causes scabies, resulting in generalized skin itching. Generally, topical medication is the main treatment, such as sulfur ointment. If the itching is obvious, you can take oral antihistamines such as loratadine and other drugs. Itchy skin all over the body, it is recommended to pay attention. Also go to the hospital for examination to find out whether it is related to drug factors, other internal diseases, it is recommended to target the primary disease treatment. Drugs need to be used in accordance with medical advice.