Ischemic foci under the cerebral cortex on both sides are lacunar cerebral infarction because the deep penetrating branches of small arteries under the cortex on both sides are ischemic, sclerotic, and occluded, resulting in local brain tissue necrosis due to ischemia, and the foci are small and usually appear in non-functional areas, and patients will not have clinical symptoms, and these are called small ischemic foci. In contrast, if the occlusion of small arteries causes necrosis of the patient’s brain tissue, the patient forms neurological deficits, such as mild limb numbness, salivation at the corners of the mouth, and other symptoms, such foci are called lacunar cerebral infarction foci. Therefore, when patients have multiple ischemic foci under the cerebral cortex on both sides, they must pay attention to the prevention of cerebral atherosclerosis in general, strictly control risk factors such as hypertension, diabetes, hyperlipidemia, etc., start secondary prevention medication for cerebrovascular disease, long-term oral BAY aspirin or Polivy antiplatelet aggregation, and oral atorvastatin to lower lipid and stabilize plaque treatment for patients with carotid plaque.