Slippage of semen is mainly caused by excessive sexual intercourse and lack of solidity of kidney qi. If the patient’s body is weak in general, with deficiency of qi and blood, or if the patient has excessive sexual intercourse, leading to the exhaustion of the lower element and the lack of solidity of the jingguan (the kidneys cannot hide the semen when the kidneys are deficient), the semen will be easy to slip and leak out, which will result in slippage of the spermatozoa. In addition, semen slippage can also be seen in dampness and heat injection, disturbing the seminal chamber, thus semen self-loss occurs. If semen slippage is caused by the lack of solidity of kidney qi, one can use the formula of Right Angelica Pill, Ginseng Ling Cuscuta Pill and Deer Antler Dazhong Tang. If it is caused by dampness-heat flowing downward and disturbing the seminal chamber, the treatment should mainly be clearing and removing dampness-heat. Use secret essence pill, big and small points clear drink and other prescription. It is recommended that patients go to a professional Chinese medicine hospital in time for the corresponding adjustment, so as to avoid the impact on life.