Overdosage or long-term use of green woodruff will produce arrow poisonous effect, gastrointestinal irritation, nephrotoxicity, cardiac inhibition and other toxic side effects. Aristolochic acid and other components, long-term overdose on the human body has certain hazards, such as arrow poisonous effect, nephrotoxicity, poisoning is mainly manifested as muscle relaxation, proteinuria, hematuria, etc.; gastrointestinal tract has an irritating effect, such as nausea, vomiting, dizziness. It also has a certain inhibitory effect on the heart. Since 2003, China has also adopted a series of risk-control measures for herbs and proprietary Chinese medicines containing aristolochic acid, including the prohibition of the use of Aristolochia sinensis, which has a high content of aristolochic acid.