If the itching of vulvar leukoplakia is serious, you can follow the doctor’s instructions to use medication to treat it, and strengthen the local skin care in daily life. The cause of vulvar leukoplakia is still unclear, easy to cause patients to appear localized itching phenomenon, severe fidgeting, affecting the quality of sleep. For those with severe localized itching, retinoids can be taken as prescribed by the doctor. For patients with chronic lichen simplex vulvar moss, the application of fludioxonil ointment, tretinoin ointment and other drugs to relieve the itching symptoms as prescribed by the doctor. For vulvar sclerosing moss, can follow the doctor’s instructions with clobetasol ointment treatment, can also apply immunosuppressant, such as tacrolimus ointment treatment, at the same time, focused ultrasound, CO2 laser and other physical therapy on the relief of vulvar leukoplakia itching is also beneficial. It is recommended that patients use medication under the guidance of a doctor, not indiscriminate use of drugs. Keep the vulvar skin clean and dry, prohibit the use of irritating drugs or soap to wash the vulva, and try to wear breathable, cotton underwear.