Dark brown blood coming out of the vagina 23 days after transplantation is considered to be possibly caused by pre-eclampsia, ectopic pregnancy, transplantation failure, etc. Treatment measures such as fertility preservation, surgery, and re-transplantation should be taken according to different situations. 1. Vaginal discharge of brown blood 23 days after transplantation is mostly caused by preeclampsia. The patient should consult a doctor promptly and take appropriate measures to preserve the fetus after examination. 2. If the fertilized egg after implantation settles outside the uterine cavity, it is an ectopic pregnancy. Most ectopic pregnancies require effective surgical treatment to avoid hemorrhage. 3. If the implantation fails for various reasons, dark brown blood will also flow from the vagina at 23 days. After the transfer has failed, the cause of the failure should be actively investigated, and the embryo transfer usually needs to be redone according to the actual situation. It is recommended to consult a doctor to find out the cause of the black-brown blood at 23 days after the transfer and treat it under the doctor’s guidance.