With the advancement of medical science, the recent survival rate of kidney transplantation has improved significantly, but the long-term survival rate has not improved significantly. There are many factors affecting the long-term effect, the most important of which are as follows: 1. 4. the difference in the patient’s primary disease affects the long-term effect of kidney transplantation; 5. the high degree of HLA compatibility has a good long-term effect of kidney transplantation; 6. the age, sex and cause of death of the donor also affect the long-term effect of kidney transplantation; 7. the difference in age and body shape of the donor and the recipient affects the long-term effect of kidney transplantation; 8. the time of preoperative dialysis and the number of kidney transplants; 9. the time, number and duration of acute rejection The influence of the time and number of reactions and the recovery of renal function; 10. The influence of different immunosuppression regimens and the degree of patient cooperation with treatment on the long-term outcome of renal transplantation.