Many patients’ blood pressure will gradually normalize or stabilize after kidney transplantation for a period of time, and the sign of stabilization is that the blood pressure can remain normal, i.e. below 140/90, when they do not take antihypertensive drugs or take 1-2 kinds of antihypertensive drugs, however, when there is a sudden change of blood pressure, we should be vigilant. Generally, blood pressure is stabilized when antihypertensive drugs are gradually stopped after renal transplantation, and then it suddenly rises from a certain point of time, and it is still difficult to return to normal with one antihypertensive drug, without obvious discomfort symptoms. This phenomenon should be vigilant, should immediately review the liver, kidney function and urine routine and transplant kidney ultrasound. There are often the following possibilities: 1, recurrence of the original kidney disease: the main manifestation is that the results of liver and renal function are not obvious abnormalities, urinary protein increased significantly, eyelids and lower limbs edema, should be reviewed as soon as possible, and if necessary, renal puncture biopsy, early treatment, early benefit; 2, acute rejection: the main manifestation is that at the same time the amount of urine is reduced, the whole body is not feeling well, creatinine is elevated, the increase in urinary protein may not be obvious, and ultrasound of transplanted kidneys will be altered, and it is important to come to the outpatient clinic for review. The results of certain antihypertensive drugs: generally speaking, angiotensin-converting enzyme inhibitor antihypertensive drugs (such as fosinopril, etc.) and angiotensin receptor blocker antihypertensive drugs (such as Irbesartan, etc.) should not be applied at the same time, such as the application of the same, which may lead to poor perfusion of the transplanted kidney, blood pressure, which will be manifested in the ultrasound, should be timely selection of other drugs to replace; 4. Renal artery stenosis: Generally speaking, renal artery stenosis will not occur after the stabilization of the function of the transplanted kidney, but sometimes due to the embodiment of changes or drastic positional changes may lead to changes in the alignment of the transplanted renal artery appearing elevated blood pressure, ultrasound of transplanted kidneys will find the problem, and may need to be hospitalized to deal with it; 5, poor lifestyle: continuous sleep deprivation or reduced quality of sleep will directly lead to elevated blood pressure, although it may seem to be one of the lightest possible , but if long-term, the body’s organs function will be affected, should try to adjust to regular, quality sleep. In addition, a diet high in salt can also lead to increased blood pressure, so it is important to eat a light diet.