Hormone shock therapy refers to a method of rapid control of the disease by applying large doses of hormones (mainly glucocorticoids such as methylprednisolone) intravenously over a short period of time. Hormone shock therapy is administered intravenously every day, such as applying methylprednisolone 500~1000mg, the intravenous drip time is not less than 1 hour, for 3~5 days, and then transitioned to oral medication, and then reduced to the maintenance amount in a few weeks. It can be used for all kinds of critical illnesses and immune diseases, such as anaphylaxis, severe renal diseases such as acute progressive glomerulonephritis. However, hormone shock therapy will appear a series of adverse reactions, such as transient hypertension and hyperglycemia, electrolyte disorders, cardiac arrhythmia, serious infections, gastrointestinal bleeding, and so on, and in severe cases, even death, and those who can not tolerate it are prohibited. Hormone shock therapy should strictly grasp the indications and contraindications, closely observe the patient’s vital signs, and timely recheck the blood routine, electrolytes and so on. The above drugs need to be used under the guidance of a doctor.