Urine protein negative with (-) number, indicating no proteinuria, urine protein characterization from (+) to (++++), this is a rough assessment of proteinuria, accurate assessment to do quantitative urine protein examination, the normal human urine protein quantitative 24 hours is less than 150 mg, physiological conditions sometimes appear urine protein (+) number, such as fever, cold, nervousness, etc., the abnormalities of this situation is generally temporary. Pathological urinary protein are caused by renal disease, common acute nephritis, chronic nephritis, nephrotic syndrome, diabetic renal damage, if there is a previous diabetes mellitus, negative urinary protein suggests normal renal function. Urine routine is only meaningful when combined with symptoms, if edema and hypertension occur, and urine protein is still negative, this test needs to be reviewed.