Interferon transaminase is good, patients with viral hepatitis B often need to use interferon to carry out antiviral treatment, in the early stages of treatment will often appear transaminase increase, indicating that the treatment is effective, is a normal phenomenon, with the improvement of the condition, transaminase can appear to decline, normalization of the change, is also a normal phenomenon, relax, continue to treat can be. Interferon is a kind of immunomodulator, in the early stage of treatment, it activates the cytokines in the body, and then enhances the function of the immune system to clear the liver cells infected by the hepatitis B virus, so the transaminase may rise, which indicates that the treatment is effective, and the rise of transaminase in this case will not exacerbate the condition, so please continue to rest assured that the treatment is safe. If the aminotransferase does not increase after using interferon, it means that the treatment is ineffective, and it is necessary to change other drugs for treatment. During the treatment period, not only the liver function and aminotransferase need to be rechecked, but also the level of hepatitis B virus DNA needs to be rechecked. If the diagnosis of viral hepatitis B is confirmed, please follow the doctor’s instructions for treatment.