It is not recommended to use this medication if the patient has red and swollen wounds, especially for open wounds or wounds that are not fully healed. This is because Podophyllotoxin is a topical drug mainly used to treat fungal infections, and this drug can also lead to skin peeling phenomenon occurs, sometimes lead to delayed healing of the wound wound infection, it is recommended that the wound is completely healed before considering the use of this drug. If it is a fungal infection, sometimes it is also necessary to use local antifungal medication, at present there are wounds do not recommend the use of podophyllotoxin.