Gastric ulcer is a relatively common disease for which there is a more established system of treatment. Gastric ulcer treatment includes medication, patient education, endoscopic treatment and surgery. The main drugs used to treat gastric ulcer are: 1. Drugs that inhibit gastric acid secretion include: H2 receptor antagonists such as famotidine, ranitidine, etc., and proton pump inhibitors (PPI) such as omeprazole, lansoprazole, etc. 2, eradication of H. pylori: the current program for the eradication of H. pylori is quadruple therapy, that is, 1 PPI + 2 antibiotics + 1 bismuth, a course of 14 days. The commonly used antibiotics are clarithromycin, amoxicillin, metronidazole furazolidone, quinolone, tetracycline. 3, gastric mucosa protective agents: bismuth, such as bismuth potassium citrate, etc., weak alkaline antacid magnesium aluminum carbonate, aluminum phosphate, aluminum hydroxide gel, etc. Patient education is also an important part of gastric ulcer treatment. Patients should take proper rest and reduce mental stress; improve eating patterns, quit smoking, alcohol and drinking less strong tea and coffee, and stop using unnecessary non-steroidal anti-inflammatory drugs, etc. Endoscopic treatment is mainly used for patients with bleeding peptic ulcer, combined with pyloric distortion or stenosis causing obstruction. With the wide application of PPI and the continuous development of endoscopic treatment technology, the treatment of most gastric ulcers and their complications no longer requires surgical intervention. However, surgical treatment should be considered in the following cases: ① when complicated peptic hemorrhage is not treated by drugs, gastroscopy and vascular intervention; ② when acute perforation and chronic penetrating ulcer are not effective; ③ when scarring pyloric obstruction is not effective by endoscopic treatment; ④ when gastric ulcer has cancerous changes. Therefore, there is a more mature treatment system for gastric ulcer, but its treatment depends on the patient’s own situation to choose different treatment modalities.