Zhi Bai Di Huang Wan does not have the efficacy of dispelling dampness and heat, its main effect is to nourish yin and reduce fire, treating conditions such as yin deficiency and fire exuberance. Zhi Bai Di Huang Wan is one of the representative formulas for nourishing yin and lowering fire, which consists of Zhi Mu, Huang Bai, Shan Yao, Cornu Cervi Pantotrichum, Radix Rehmanniae Praeparata, Mudan Pi, Zedoariae, and Poria. In the formula, Liu Wei Di Huang Wan has the effect of nourishing kidney yin, and the addition of Huang Bai and Zhi Mu enhances the effect of nourishing yin and clearing fire. Zhi Bai Di Huang Wan is mainly used in the treatment of hot flashes and excessive sweating, irritability, insomnia, lumbar and knee pain, and spermatorrhea in men caused by kidney yin deficiency and fire exuberance. Zhi Bai Di Huang Wan does not have the effect of dispelling dampness-heat. Clinical herbal formulas to dispel dampness-heat include San Ren Tang, Er Miao San, Si Miao Wan, and so on. The specific use of drugs need to consult a professional physician, not blindly use their own medication, in order to avoid adverse reactions.