Clinically, there is no effective treatment for children’s nighttime coughing. Consider the possibility of pneumonia, upper respiratory tract infections, cough variant asthma, etc., and after diagnosis, you can be treated with general therapy and medication. 1. Pneumonia: some special pathogens of pneumonia, such as mycoplasma pneumonia, as well as whooping cough pneumonia, often manifested in the night as well as early morning cough is more obvious, you can improve the sputum nucleic acid PCR examination to clarify the diagnosis, and then follow the doctor’s instructions to be azithromycin anti-infective treatment, in addition to supplemented with budesonide, aminobromine, salbutamol nebulizer inhalation, dilate the airway, sputum. 2. Respiratory tract infections: As respiratory tract infections can cause localized inflammatory reactions in children, inflammatory stimuli may cause cough. If the cough is caused by bacterial infection, you can take antibiotics as prescribed by the doctor, such as cefixime, amoxicillin, etc. You can also take cough suppressants and phlegm removers, such as aminoglutethimide hydrochloride, etc., under the guidance of the doctor. 3. Cough variant asthma: If exposure to allergens leads to airway smooth muscle contraction caused by cough variant asthma, manifested as irritating dry cough, night and early morning cough obvious, the need for long-term nebulizer inhalation therapy, can be given budesonide, salbutamol nebulizer inhalation therapy as prescribed by the doctor. There are many reasons why children cough at night, should go to the hospital in time, after a clear diagnosis of the cause of the disease, and then targeted treatment, they can not blindly use drugs, so as not to cause other damage.