In clinical practice, it is common to use closed injections for the treatment of various acute and chronic aseptic inflammatory diseases. How effective is the closed needle needs to be clarified, first of all, under the standardized use of closed needle treatment, the standardized use of medication dosage. Closed injections are perfectly feasible and very effective. Closed needle due to contain a certain amount of glucocorticoid drugs, so can not be used frequently, if the use of too many times, the dose is too large, will produce more obvious side effects, and even easy to lead to aseptic necrosis of the femoral head, leading to generalized obesity, full moon face, buffalo back and other side effects. But as long as the standardized use of medication, standardize the dose of medication, is absolutely no problem.