Because early clinical diagnosis of PD is difficult, the time for early treatment of PD is often lost. Medical research has shown that clinical treatment for PD consists of three main aspects: 1) symptomatic treatment, which is to improve clinical symptoms and delay disease progression; 2) neuroprotective treatment, which is to improve the natural course of the disease and prevent further development; 3) neuroprosthetic treatment, which is to restore neurons that have been degenerated in the brain (gene therapy). Currently, symptomatic treatment and partial neuroprotective treatment for PD are often used in clinical practice. Although we have not been able to cure PD and there is no ideal drug, doctors usually implement treatment according to PD clinical treatment guidelines. Specific medication principles: 1. All anti-PD drugs are dosed by dose titration to avoid the occurrence of recent side effects; 2. There has been academic controversy on whether levodopa agents (e.g. Medroba or Xanax) or dopamine agonists (e.g. Sempranol, Tysudar) are preferred for early treatment of PD. Many scholars currently believe that dopamine agonists should be preferred as the starting treatment for PD in patients aged ≤65 years. When clinical efficacy wanes, levodopa preparations are started to maintain a more satisfactory quality of life and prolong the life span of PD patients, thus achieving the therapeutic goal of PD. If the “end-of-dose phenomenon” occurs after treatment, it is recommended to add levodopa at the same time, which can increase the utilization of levodopa to optimize levodopa to relieve the end-of-dose phenomenon, and also add dopamine agonists and monoamine oxidase B inhibitors to improve disease fluctuation disorder, delay and postpone the onset of isokinetic disorder. In conclusion, the author believes that the treatment of PD is a process of fine-tuning the dose of anti-PD drugs to: 1) clarify the diagnosis; 2) choose the right time to start treatment; 3) choose drug therapy rationally; 4) the treatment plan should be individualized.