There is no exact time for the symptoms of epilepsy (seizures) to disappear after craniotomy, which is closely related to the patient’s own condition as well as the treatment, and most patients can usually disappear in about 3 to 7 days. In some patients, localized brain tissue contusion, edema, and poor venous return after craniotomy lead to epilepsy within a short period of time after surgery. In this case, taking antiepileptic drugs according to the doctor’s instruction for treatment, epileptic symptoms usually can basically disappear after the cerebral edema is eliminated within 3 to 7 days. In some patients, after craniotomy, structural changes gradually appear in the brain, such as localized softening foci of brain tissue, gliosis or scarring, and epilepsy appears long after the operation. At this time, it is difficult to control the condition through antiepileptic drugs, and it is necessary for the doctor to carry out a perfect assessment of the condition, and if necessary, surgery may be needed to resect the foci to control epilepsy, and in this case, epilepsy disappears over a longer period of time. At the same time, it is recommended that patients take antiepileptic drugs on time after craniotomy, pay attention to rest, avoid irritating, spicy and greasy food, and pay attention to nutrition, which will help their condition recover.